Assoc. Prof. Dr. Ampai Panthong
Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
and Mangosteen Research and Development Center, Asian Phytoceuticals Public Co., Ltd.

Xanthones in mangosteen posses anti-inflammatory activity and the most active one is GM-1. The detailed study of GM-1 for its anti-inflammation and analgesia showed that GM-1 exhibited stronger anti-inflammatory activity three times over that of aspirin as seen in carrageenin-induced rat paw edema, rat pleurisy and on the primary lesion of adjuvant-induced arthritis models. In addition GM-1 also showed inhibitory activity in chronic inflammation as found in cotton pellet-induced granuloma formation and on the secondary lesion of adjuvant-induced arthritis in rats. Furthermore GM-1 elicited analgesic effect when tested in acetylcholine-induced writhing response in mice. The investigation of analgesic effect of the products from mangosteen (as food supplement) in volunteers with joint pain and gastric ulcer will also be presented.

  • Lab Data of BIM Capsule and BIM Mangosteen Juice
  • Antioxidation and antimalarial activities of xanthones from mangosteen
  • Anti-bacterial activities of xanthones from mangosteen
  • Anti-inflammation of xanthones from mangosteen
  • Molecular investigation on anti-cartilage degradation by xanthones from mangosteen
  • Mangosteen products: from the lab bench to the world market
  • Operation BIM : Presented in the 34th CONGRESS on SCIENCE and TECHNOLOGY of THAILAND (STT 34),
    30 October, 2008